Phytocannabinoids

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When I started researching cannabis there was one problem I experienced over and over and over again. Which was an accurate list of the physical, chemical, and biological properties of the mayor and minor cannabinoids found in Cannabis sativa L. This section of the site will be dedicated to providing the most accurate and precise details of the most common phytocannabinoids (plant derived cannabinoids).

The information provided on each cannabinoid will be divided into three main parts:

Chemical Information – In this section we will provide the actual IUPAC name, chemical formula, molecular weight.

Properties – These are the actual characteristics of the isolated compounds. Included in these descriptions are the color, original state (solid, liquid, gas), boiling temperatures at sea level 1 atmosphere), and density. Additionally, we will provide short (4 weeks) and long-term stability (12-60 months) information, such as ideal storage temperatures to prevent degradation, and degradation rate at specific temperatures over time.

Biology – Although the studies conducted on cannabinoids is ever changing, in this section we will provide the established therapeutic properties of these compounds in humans. This includes the results from well conducted clinical trials, dosages, and other potential applications. We will not include data from in vitro work because of the often contradictory and inconsistent nature of these studies.

As a bonus download, I am also including a free copy of the 2D and 3D molecular structures. Each molecule was personally designed using ChemDraw.

Thanks largely to the work performed in Israel during the 1960’s, we have been ushered into the golden age of cannabis science. Although, THC largely received the most attention for many years, the remarkably complex chemical and pharmacological profiles of different cannabis cultivars have recently been explored. Being led first by the popular CBD, followed by an extensive list of minor cannabinoids that all interact synergistically with each other. It has largely been accepted that “the whole is greater than the sum of its parts”, which means that the entire cannabinoid profile provides better therapeutic efficacy than each compound individually.

You may be asking yourself, what about all those terpenes?

Let’s make one thing clear…although well-meaning, the research suggesting that terpenes possess any significant therapeutic effect is tenuous at best, bad science at worst. So long as no concrete scientific proof is provided demonstrating real therapeutic efficacy for terpenes found in cannabis, we will not be discussing them in this site. If you think that what I am saying is factually incorrect, I invite you to dig around and investigate this topic for yourselves. I welcome anyone with solid scientific facts to contact me with their results.

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